Ozempic vs Wegovy, Mounjaro vs Zepbound: Same Medicine, Two Labels

Short answer: Ozempic® and Wegovy® both contain semaglutide. Mounjaro® and Zepbound® both contain tirzepatide. Each brand has its own FDA label, with its own approved uses, forms and instructions. The brand name tells you which label your prescriber is working from, so it is worth knowing which one you have. This page compares the labels as they appeared on DailyMed on October 30, 2026. Brand names are used here only to identify the medicines. This site is not affiliated with their makers.

What is the generic name for Ozempic, Wegovy, Mounjaro and Zepbound?

The active ingredient is the generic name:

Brand	Active ingredient (generic name)
Ozempic	Semaglutide
Wegovy	Semaglutide
Rybelsus	Semaglutide
Mounjaro	Tirzepatide
Zepbound	Tirzepatide

Why does one ingredient have several brands? Each brand was approved with its own label, and a label states the uses the maker studied and the FDA reviewed for that brand. Whether a given pharmacy can substitute one product for another is a question for your prescriber and pharmacist, not something this page can answer.

How do Ozempic and Wegovy differ?

Both labels say the medicine is a GLP-1 receptor agonist containing semaglutide. The differences are in what each label covers.

	Ozempic	Wegovy
Main use on the label	Adults with type 2 diabetes: improve glycemic control; reduce certain cardiovascular and kidney risks	Weight: reduce excess body weight and maintain weight reduction in adults with obesity or overweight plus a weight-related condition, and in patients 12 and older with obesity; also reduce cardiovascular risk in certain adults and treat noncirrhotic MASH in adults
Used with	Diet and exercise	A reduced calorie diet and increased physical activity
Forms listed in Section 3	Single-patient-use pens with multiple weekly doses; single-dose prefilled syringes	Single-dose pens and syringes, a single-patient-use pen, and tablets

The Wegovy label’s Limitations of Use say that using Wegovy “with other semaglutide-containing products or with any other GLP-1 receptor agonist is not recommended.” Ozempic tablets also exist: a DailyMed label dated August 19, 2026 covers Rybelsus and Ozempic tablets together.

How do Mounjaro and Zepbound differ?

	Mounjaro	Zepbound
Main use on the label	Adults and pediatric patients 10 and older with type 2 diabetes: improve glycemic control; reduce major cardiovascular events in certain adults with type 2 diabetes	Adults with obesity or overweight plus a weight-related condition: reduce excess body weight and maintain weight reduction; moderate to severe obstructive sleep apnea in adults with obesity
Used with	Diet and exercise	A reduced-calorie diet and increased physical activity
Forms listed in Section 3	Single-dose pens, single-dose vials, multi-dose vials and single-patient-use KwikPens	The same four forms

The two labels list largely the same warnings and the same storage conditions, with the hypoglycemia wording adapted to each use. The clearest difference is the list of approved uses.

Why does it matter which brand you have?

Three practical reasons:

• Insurance: coverage rules can depend on the brand and on the use. A weight-management label and a diabetes label are different labels. Ask your plan which brand and which use it covers.
• Instructions: each brand has its own Instructions for Use and Medication Guide. Use the ones that came with your pen or vial.
• Safety information: both labels in each pair carry the same kind of boxed warning about thyroid C-cell tumors seen in rodents, and the same kinds of stomach and bowel side effects. See GLP-1 side effects.

How does semaglutide compare with tirzepatide?

That is a different question: the two ingredients work on different receptors. See Tirzepatide vs semaglutide: what the labels and a trial say.

How can you remember which brand you take?

A short note with the brand name, the form (pen, vial or tablet), the date and the injection area helps at pharmacy pick-up and at appointments. For rotating areas, see GLP-1 injection sites. Weeko, a shot tracker coming to iPhone and Android, is being built around this kind of simple log. It is a logbook, not medical guidance.

When to call your doctor

Talk to your prescriber or pharmacist before switching brands, combining GLP-1 medicines, or stopping one. Get emergency care for severe stomach pain, signs of an allergic reaction such as swelling of the face or throat, or trouble breathing.